Estrogen is one of the primary hormones involved in a woman’s menstrual cycle. When estrogen levels are healthy and balanced, it helps optimize neurotransmitter production and brain function so you feel good all month long. When estrogen levels are off, it causes problems.

Too much estrogen in relation to progesterone can lead to a condition called estrogen dominance. This causes the gentle monthly hormonal rise and fall to turn into a series of intense spikes and dramatic drop-offs that disrupt important brain processes and make you anxious and irritable.

Too little estrogen leads to feeling depressed and confused. The loss of estrogen also hinders critical thinking, short-term memory, and other cognitive functions. These problems can worsen during perimenopause when estrogen levels can fluctuate wildly and during menopause when the hormone drops and stays low.


• Mood swings, depression
• Fatigue
• Sluggish metabolism
• Low libido
• Headaches or migraines
• Brain fog, memory loss
• Weight gain, especially in the belly and hips
• Thyroid dysfunction
• Sleep disturbances
• Fibrocystic breasts
• Bloating
• Vaginal or oral yeast (thrush)
• Heavy bleeding
• Carbohydrate cravings

• Mood changes, depression, weepiness
• Fatigue
• Heart palpitations
• Osteoporosis
• Painful intercourse
• Brain fog, memory loss, focus problems
• Weight gain
• Bladder incontinence and infections
• Sleep disturbances
• Pain
• Hot flashes